{"product_id":"fc-receptor-panel","title":"Fc Receptor Panel","description":"\u003cp\u003eThe \u003cstrong\u003eFc Receptor Panel\u003c\/strong\u003e is a ready-to-use multiplexed binder set for the MACS Matchmaker focal molography platform. It profiles the full Fcγ receptor family alongside the high- and low-affinity IgE receptors on a single chip in approximately one hour.\u003c\/p\u003e\n\n\u003cp\u003eThe panel runs on the \u003ca href=\"\/products\/sensor-2d-peg-oligo-peg-8-plex\"\u003eSensor [Oligo|PEG] 8-plex\u003c\/a\u003e with seven pre-conjugated Fc receptors at fixed oligonucleotide sequences 1–7, plus an oligo-only construct on slot 8 that mimics the DDI interface without a captured receptor. The reference slot supports DNA-layer non-specific binding subtraction; authentic Fc-mediated signals on slots 1–7 produce no response on this channel.\u003c\/p\u003e\n\n\u003ch3\u003ePanel composition\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003eFcγRI (CD64), human, activating high-affinity\u003c\/li\u003e\n\u003cli\u003eFcγRIIa (CD32a), human, activating\u003c\/li\u003e\n\u003cli\u003eFcγRIIb (CD32b), human, inhibitory\u003c\/li\u003e\n\u003cli\u003eFcγRIIIa (CD16a), human, activating\u003c\/li\u003e\n\u003cli\u003eFcγRIIIb (CD16b), human, GPI-anchored activating\u003c\/li\u003e\n\u003cli\u003eFcεRI, human, high-affinity IgE receptor\u003c\/li\u003e\n\u003cli\u003eFcεRII (CD23), human, low-affinity IgE receptor\u003c\/li\u003e\n\u003cli\u003eComplementary oligonucleotide (oligo-only NSB reference)\u003c\/li\u003e\n\u003c\/ol\u003e\n\n\u003cp\u003eFor antibody half-life and FcRn cross-species characterization, see the separate \u003ca href=\"\/products\/fcrn-species-panel\"\u003eFcRn Species Panel\u003c\/a\u003e (pH-switch single-cycle kinetics workflow, six FcRn species, runs on the same MACS Matchmaker instrument).\u003c\/p\u003e\n\n\u003ch3\u003eApplications\u003c\/h3\u003e\n\u003cp\u003eFor applications, workflow, kinetic benchmarks, allotype-extended chip configuration (FcγRIIa H131\/R131, FcγRIIIa V158\/F158) and references, see the \u003ca href=\"https:\/\/www.lino-biotech.com\/applications\/fc-receptor-panel\"\u003e\u003cstrong\u003eFc Receptor Panel application page\u003c\/strong\u003e\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e pre-conjugated receptor mix, NHS-conjugated DDI oligos\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVolume:\u003c\/strong\u003e 110 µL\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConcentration:\u003c\/strong\u003e 2.6 µM per ligand\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjections:\u003c\/strong\u003e 10 (at 200 nM, 130 µL injection volume)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage solution:\u003c\/strong\u003e PBS-T\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBuilt-in QC:\u003c\/strong\u003e oligo-only reference channel on slot 8 for direct DNA-layer NSB subtraction\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not for diagnostic or therapeutic procedures.\u003c\/em\u003e\u003c\/p\u003e","brand":"lino Biotech AG","offers":[{"title":"8-plex, 7 receptors + NSB reference","offer_id":57088339411319,"sku":"MRA-FcRPanel-10.B08","price":1526.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0915\/3524\/5687\/files\/Fc_Receptor_Panel_Overview.png?v=1778686819","url":"https:\/\/shop.lino-biotech.com\/products\/fc-receptor-panel","provider":"lino Biotech AG","version":"1.0","type":"link"}