Multiplexed Panels

Multiplexed panels of pre-conjugated capture molecules, ready for parallel measurement of multiple targets on a single sensor chip.

Every panel works the same way. Each capture molecule carries its own sequence-specific oligonucleotide, and every position on a MACS Matchmaker sensor chip carries the complementary capture strand. A single injection of the panel therefore loads all channels at once by DNA-directed immobilization (DDI), with each ligand finding its own position. No coupling chemistry at the bench, and no separate run per ligand.

The sample is then injected across the whole chip and every interaction is recorded label-free and in real time. Because all channels see the same sample on the same surface at the same moment, the readouts are directly comparable within one measurement instead of across runs. Where the assay calls for it, a panel carries its own reference or control channel, so non-specific binding is subtracted from that same injection.